The i-WIP Collaborative Group was established in 2013 and an international group of researchers who conducted trials on the effect of diet and physical activity based interventions in pregnancy. The group’s main aim was to deliver an Individual Participant Data meta-analysis addressing the question of the lifestyle-based intervention’s effect on gestational weight gain, maternal and offspring outcomes.
The IPPIC (International Prediction of Pregnancy Complications) collaborative network consists of individual participant data (IPD) of over 3 million pregnancies. This large global repository originally funded by the NIHR HTA (National Institute of Health Research Health Technology Assessment) to predict pre-eclampsia, includes 14 UK and 66 international datasets. It has since received further funding from Sands (Stillbirth and Neonatal Deaths) charity to predict stillbirth, NHMRC (Australian National Health and Medical Research Council) to predict preterm birth and HTA to predict fetal growth restriction and its complications.
The SALVO study was led by our Centre and published in 2017 – it was the largest ever randomised controlled trial on the use of cell salvage in obstetrics. Over 3000 women across the UK were randomised to either receive cell salvage in the event of bleeding in childbirth, or standard of care. The primary objective was to find out if routine cell salvage use has the potential to reduce the need for donor blood transfusion.
To find out more and read about the results, see https://discover.dc.nihr.ac.uk/content/signal-00592/cell-salvage-during-c-section-doesnt-reduce-blood-transfusions or download our SALVO newsletter